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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNE1 All Species: 23.33
Human Site: S103 Identified Species: 39.49
UniProt: P24864 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P24864 NP_001229.1 410 47077 S103 I I A P S R G S P L P V L S W
Chimpanzee Pan troglodytes XP_512559 393 44800 E97 L S W A N R E E V W K I M L N
Rhesus Macaque Macaca mulatta XP_001084995 410 47103 S103 I I A P S R G S P L P V L S W
Dog Lupus familis XP_541724 456 51105 S149 S F M P S R A S P L P L L N W
Cat Felis silvestris
Mouse Mus musculus Q61457 408 46968 A100 R K I R P P R A S P L P V L N
Rat Rattus norvegicus P39949 411 47463 A103 R K I R P P R A S P L P V L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507249 405 46635 S101 K N L F I N P S P L P D L S W
Chicken Gallus gallus P49707 407 46720 S100 N V A S T R S S P L P I L G W
Frog Xenopus laevis Q91780 408 47153 S102 R F S P V S V S P L P R L G W
Zebra Danio Brachydanio rerio P47794 410 46612 T105 F I T P T R S T P L P A L C W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54733 709 77202 C318 V E N G L R Q C P L P A L A W
Honey Bee Apis mellifera XP_394802 457 51232 S105 P S S S N N T S N R P S P L P
Nematode Worm Caenorhab. elegans O01501 524 60567 Y193 E S E D E D D Y P V Q N E G F
Sea Urchin Strong. purpuratus XP_785047 424 48468 S114 A H V S D R A S P V P L L H W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.3 98.2 73.9 N.A. 78.7 79.5 N.A. 49 71.9 60.2 58.2 N.A. 28.2 38.2 24.2 44.5
Protein Similarity: 100 95.3 98.5 81.1 N.A. 88.7 90 N.A. 66.5 85.1 76.8 73.9 N.A. 39.6 55.1 41.4 60.8
P-Site Identity: 100 6.6 100 60 N.A. 0 0 N.A. 46.6 53.3 46.6 53.3 N.A. 40 13.3 6.6 40
P-Site Similarity: 100 33.3 100 73.3 N.A. 13.3 13.3 N.A. 46.6 73.3 53.3 66.6 N.A. 53.3 26.6 20 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 22 8 0 0 15 15 0 0 0 15 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 8 8 8 8 0 0 0 0 8 0 0 0 % D
% Glu: 8 8 8 0 8 0 8 8 0 0 0 0 8 0 0 % E
% Phe: 8 15 0 8 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 8 0 0 15 0 0 0 0 0 0 22 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 15 22 15 0 8 0 0 0 0 0 0 15 0 0 0 % I
% Lys: 8 15 0 0 0 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 8 0 8 0 8 0 0 0 0 58 15 15 65 29 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 8 8 8 0 15 15 0 0 8 0 0 8 0 8 22 % N
% Pro: 8 0 0 36 15 15 8 0 72 15 72 15 8 0 8 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % Q
% Arg: 22 0 0 15 0 58 15 0 0 8 0 8 0 0 0 % R
% Ser: 8 22 15 22 22 8 15 58 15 0 0 8 0 22 0 % S
% Thr: 0 0 8 0 15 0 8 8 0 0 0 0 0 0 0 % T
% Val: 8 8 8 0 8 0 8 0 8 15 0 15 15 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 65 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _